Monday, May 13, 2019
DYSLIPIDEMIA Assignment Example | Topics and Well Written Essays - 750 words
DYSLIPIDEMIA - Assignment ExampleDys lipideemia is an important component of the clop of abnormalities in metabolic syndrome, basically implying an imbalance of lipids in circulation in the blood stream (Ruotolo & Howard, 2002). Dyslipidemia is characterized by increase triglycerides, lower high-density lipoprotein cholesterol, HDLc, postprandial accumulation of lipoproteins rich in triglyceride and small, low density lipoproteins, LDL. It involves reesterification, this being the process of circulate free fatty acids getting oxidized and then synthesized back into triglyceride.Being a component of a syndrome related to many risk factors, metabolic syndrome, dyslipidemia presents a complex pathology. Even so, Foster and Prevost (2012) cite aerophilous stress as a key hypothesis regarding the pathology of dyslipidemia. Oxidative stress, referring to the surplus of reactive oxygen species, ROS to antioxidant, fosters insulin rampart. This could put across because of excessive prod uction of ROS which would overwhelm the capacity of ROS antioxidant or decrease production of antioxidants to inactivate ROS. Obesity has excessively been cited as a metabolic predisposition which eventually leads to dyslipidemia. Genetics also affects metabolic predisposition to resistance to insulin and dyslipidemia.Dyslipidemic conditions require laboratory testing to establish the specific abnormal blood lipid content or the lipoprotein content. As much(prenominal), laboratory testing would involve measuring a blood sample for blood lipid profile and should be done every 5 years from as early as years 20. The levels of LDLc could be determined directly or using the Friedwald formula given byThis formula would except not be applied in cases where the triglyceride level of an individual exceeds 400 mg/dl. Notably, the basic lipid profile totaling triglyceride, HDLc and LDLc could fail to provide a clinician with adequate information to effectively diagnose dyslipidemia. In suc h cases, more sophisticated procedures
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